Investigating the Role of Transcription Factor AP-2ß in Modulating Corneal Epithelial Stratification

研究转录因子 AP-2™ 在调节角膜上皮分层中的作用

• 批准号: 490919
• 负责人: Antolin Joel
• 金额: $ 1.27万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=490919&lang=en
• 关键词: Ap-2b; B-Catenin; Bmp4; Cornea; Development; Epithelium; Signaling; Stratification; Stroma; Wnt

The cornea, which is the outermost part of the anterior eye, is composed of an outer stratified epithelium, an inner endothelium, and a stroma located between these layers. Development of these corneal layers are dependent on activating protein 2ß (AP-2ß)

角膜是前眼的最外层，由外层的层状上皮、内部的内皮和层间的间质组成。这些角膜层的发育依赖于活化蛋白2ß （AP-2ß）。