Epigenetic Drivers in Metastatic Melanoma and Chromatin Loop-Specific Targeting Strategies

转移性黑色素瘤的表观遗传驱动因素和染色质环特异性靶向策略

• 批准号: 479089
• 负责人: Orouji Elias
• 金额: $ 57.12万
• 依托单位: University Health Network (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2023
• 资助国家: 加拿大
• 起止时间: 2023-03-01 至 2028-03-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=479089&lang=en
• 关键词: Chromatin Architecture; Epigenomics; Melanoma; Metastasis

Melanoma is the most lethal type of skin cancer with an increasing annual incidence rate in Canada. A major challenge in the treatment of melanoma is the aggressive nature of tumor cells and their ability to invade other body organs, a process known as "m

黑色素瘤是最致命的皮肤癌类型，在加拿大的年发病率不断增加。治疗黑色素瘤的一个主要挑战是肿瘤细胞的侵袭性和它们侵入其他身体器官的能力，这一过程被称为“恶性黑色素瘤”。