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Sex and sex-hormones determine pulmonary morphological and single-nucleus transcriptomic responses in an animal model of sleep apnea.

Sex and sex-hormones determine pulmonary morphological and single-nucleus transcriptomic responses in an animal model of sleep apnea.
性和性激素决定睡眠呼吸暂停动物模型中的肺部形态和单核转录组反应。
批准号:
494508
负责人:
Joseph Vincent
金额:
$7.29万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
已结题
起止时间:
2023-09-01 至 2024-09-01

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中文摘要
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英文摘要
Sleep apnea is a common respiratory disorder occurring as the airflow to the lungs is obstructed by the closure of the upper airways (in the neck). This may last from several seconds and up to > 1 minute, during which oxygen levels in the blood drop rapid
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Apnea, sex and FMO: Are flavin-containing monooxygenases the new anti-ox that prevent metabolic disorders under intermittent hypoxia?
  • 批准号:
    487678
  • 项目类别:
    Operating Grants
  • 资助金额:
    $46.26万
  • 财政年份:
    2023
  • 负责人:
    Joseph Vincent
  • 依托单位:
Estradiol receptor alpha mediates sex-specific responses in an animal model of sleep apnea.
  • 批准号:
    389766
  • 项目类别:
    Operating Grants
  • 资助金额:
    $46.26万
  • 财政年份:
    2018
  • 负责人:
    Joseph Vincent
  • 依托单位:
Age- and sex-specific contribution of nuclear or membrane progesterone receptors on respiratory control in mice.
  • 批准号:
    265347
  • 项目类别:
    Operating Grants
  • 资助金额:
    $44.27万
  • 财政年份:
    2012
  • 负责人:
    Joseph Vincent
  • 依托单位:
A critical role of progesterone for development of respiratory control system.
  • 批准号:
    188430
  • 项目类别:
    Operating Grants
  • 资助金额:
    $26.94万
  • 财政年份:
    2009
  • 负责人:
    Joseph Vincent
  • 依托单位:
海外基金