Determination of lung morphology from X-ray phase contrast radiographs

通过 X 射线相衬 X 线照片确定肺形态

• 批准号: DP0878483
• 负责人: A/Prof Marcus Kitchen
• 金额: $ 17.03万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-03-20 至 2011-07-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0878483
• 关键词: Determination; lung; morphology; ray; phase

Current methods of imaging the lung rely heavily on low contrast images obtained with chest radiography or computed tomography. This research will develop new X-ray phase contrast imaging techniques capable of providing a tenfold contrast increase over conventional chest radiography at a fraction of the X-ray dose of computed tomography. Methods of extracting quantitative information on lung morphology and pathology from phase contrast chest radiographs will be developed during this research. Eventual outcomes are likely to lead to improved methods of detecting lung disease and injury for both biomedical and clinical studies.

目前的肺部成像方法严重依赖于胸部X线摄影或计算机断层扫描获得的低对比度图像。这项研究将开发新的X射线相衬成像技术，能够提供一个十倍的对比度增加超过传统的胸部X射线摄影的一小部分的X射线剂量的计算机断层扫描。在本研究中，将开发从相位对比胸片中提取肺形态和病理定量信息的方法。最终的结果可能会导致改进的方法来检测肺部疾病和损伤的生物医学和临床研究。