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Structural Basis of Aberrant cAMP Signaling and of PKA-Targeting Therapies

Structural Basis of Aberrant cAMP Signaling and of PKA-Targeting Therapies
异常 cAMP 信号传导和 PKA 靶向治疗的结构基础
批准号:
495044
负责人:
Melacini Giuseppe
金额:
$7.29万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
已结题
起止时间:
2023-09-01 至 2024-09-01

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中文摘要
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英文摘要
Protein Kinase A (PKA) plays a key role in controlling cellular metabolism. Genetic PKA mutations impair its ability to regulate cells, resulting in a general predisposition for pancreatic, endocrine, and cardiac tumors, as well as developmental disorders
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Structural Basis of Cyclic Nucleotide Signal Translation and Inhibition
  • 批准号:
    483395
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2023
  • 负责人:
    Melacini Giuseppe
  • 依托单位:
Structural Basis of Cyclic Nucleotide Signal Translation
  • 批准号:
    472447
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2022
  • 负责人:
    Melacini Giuseppe
  • 依托单位:
Structural Basis of Cyclic Nucleotide Signal Translation and Inhibition
  • 批准号:
    369883
  • 项目类别:
    Operating Grants
  • 资助金额:
    $75.24万
  • 财政年份:
    2017
  • 负责人:
    Melacini Giuseppe
  • 依托单位:
Structural Basis of cyclic AMP-Signal Translation in Eukaryotes by Nuclear Magnetic Resonance
  • 批准号:
    252408
  • 项目类别:
    Operating Grants
  • 资助金额:
    $58.48万
  • 财政年份:
    2012
  • 负责人:
    Melacini Giuseppe
  • 依托单位:
海外基金