Decoding how the aryl hydrocarbon receptor (AhR) controls cigarette smoke-induced lung inflammation and development of chronic obstructive pulmonary disease (COPD)

解读芳烃受体 (AhR) 如何控制香烟烟雾引起的肺部炎症和慢性阻塞性肺病 (COPD) 的发展

• 批准号: 487508
• 负责人: Baglole Carolyn
• 金额: $ 68.55万
• 依托单位: Research Institute of the McGill University Health Centre
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2023
• 资助国家: 加拿大
• 起止时间: 2023-09-01 至 2028-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=487508&lang=en
• 关键词: Aryl Hydrocarbon Receptor; Chronic Obstructive Pulmonary Disease; Cigarette Smoke; Inflammation

The aryl hydrocarbon receptor (AhR) is a protein found in almost all of the cells in our body. Much of what is known about the AhR centers on its ability to cause toxic effects of man-made environmental chemicals called dioxins. There is growing evidence

芳香烃受体(AhR)是一种蛋白质，存在于我们体内几乎所有的细胞中。人们对AhR的大部分了解都集中在它对人造环境化学物质二恶英的毒性影响上。有越来越多的证据表明