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Defining the role of monocytes in protective immunity against healing and non-healing Leishmaniasis: implications for treatment and vaccination against phagosomal pathogens.

Defining the role of monocytes in protective immunity against healing and non-healing Leishmaniasis: implications for treatment and vaccination against phagosomal pathogens.
定义单核细胞在针对愈合和非愈合利什曼病的保护性免疫中的作用：对吞噬体病原体的治疗和疫苗接种的影响。
批准号：
495111
负责人：
Peters Nathan
金额：
$7.29万
依托单位：
University of Calgary
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2023
资助国家：
加拿大
项目状态：
已结题
起止时间：
2023-09-01 至 2024-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=495111&lang=en
关键词：
Clinical Isolates Intracellular Pathogens Leishmania Monocytes Non-Healing Disease Phagosomal Infections T Cells Tnfr Superfamily Vaccination

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中文摘要
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英文摘要
The objective of this grant is to gain a better understanding of the mechanisms of infected cell activation in settings of pre-existing T helper 1 (Th1)/Cell-mediated immunity (prior infection, vaccination) against phagosomal infections. Specifically the
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Mechanisms of Leishmania dissemination and transit in the mammalian host following vector transmission
  • 批准号：
    403205
  • 项目类别：
    Operating Grants
  • 资助金额：
    $73.56万
  • 财政年份：
    2019
  • 负责人：
    Peters Nathan
  • 依托单位：
    University of Calgary
Redefining mechanisms of protective immunity against Leishmania infection - towards a novel vaccination strategy
  • 批准号：
    323680
  • 项目类别：
    Operating Grants
  • 资助金额：
    $58.13万
  • 财政年份：
    2015
  • 负责人：
    Peters Nathan
  • 依托单位：
    University of Calgary
海外基金