Regulation of protein synthesis in the mammalian hippocampus via putative mRNA targets of miR-9 and its impact on synaptic plasticity, learning and memory.

通过 miR-9 的推定 mRNA 靶标调节哺乳动物海马中的蛋白质合成及其对突触可塑性、学习和记忆的影响。

• 批准号: 200356
• 负责人: Henderson Valerie C
• 金额: $ 1.27万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-02-01 至 2011-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=200356&lang=en
• 关键词: Electrophysiology; Hippocampus; Lentiviral Transfection; Long-Term Potentiation; Memory; Microrna; Neurodegenerative Diseases; Protein Synthesis; Rodent Behaviour; Synaptic Plasticity

The hippocampus in the mammalian brain is responsible for many kinds of learning and the formation of long-term memories. The main process whereby this occurs is called Long-Term Potentiation (LTP). This process is tightly controlled by an intricate netwo

哺乳动物大脑中的海马体负责多种学习和长期记忆的形成。这一过程被称为长时程增强（LTP）。这个过程是由一个复杂的网络严密控制的。