Immune driven changes in colonic epithelial cell differentiation: Pathophysiology or a novel mechanism of host defense?

免疫驱动的结肠上皮细胞分化变化：病理生理学还是宿主防御的新机制？

• 批准号: 202518
• 负责人: Chan Justin M
• 金额: $ 1.27万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-02-01 至 2011-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=202518&lang=en
• 关键词: Adaptive Immune System; Citrobacter Rodentium; Enterohemorrhagic Escherichia Coli; Enteropathogenic Escherichia Coli; Goblet Cell; Host Defense; Inflammatory Disease; Intestinal Epithelial Cells; Notch; Proliferation

Our intestinal tract is lined with many different kinds of cells, each with their own unique role. The intricacy of our gut requires a carefully monitored balance of cell growth and death known as cell turnover. Many gut-related diseases throw off this

我们的肠道内排列着许多不同种类的细胞，每种细胞都有自己独特的作用。 我们肠道的复杂性需要仔细监测细胞生长和死亡的平衡，称为细胞更新。 许多与肠道有关的疾病都摆脱了这一点，