电针“曲池”、“足三里”改善脑卒中后运动功能，临床疗效确切，已被广泛应用。前期研究从RA信号通路调控内源性NSCs增殖及G-蛋白调控钙、钾通道抑制神经递质GABA的释放等方面，肯定了电针改善神经缺损功能的脑保护作用，但局限于离体、局部、静态、孤立的脑区，且其中枢作用机制尚不十分明确。本研究拟以MCAO模型大鼠为研究对象，采用7.0T功能核磁（ fMRI）观察电针“曲池”、“足三里”脑区的核磁信号变化，从整体、功能、动态的角度探讨电针“曲池”、“足三里”改善脑卒中后运动功能障碍的中枢机制，同时结合透射电镜观察电针“曲池”、“足三里”对神经突触形态学的影响，进一步提供可视性的实验依据，为临床应用治疗提供理论基础。

Electro-acupuncture at "Quchi (LI 11)", "Zusanli(ST 36)" improves the motor function after cerebral apoplexy, the clinical curative effect is exact, and it has been widely used. The preliminary affirmed the brain protective effect of electro-acupuncture in improving the neurologic deficit, from the aspect as follow: RA signaling pathways regulated endogenous NSCs proliferation, the calcium regulation by G protein, potassium channel inhibitted the release of the neurotransmitter GABA, etc. But all of these confined to in vitro, local, static, isolated brain regions, and the mechanism of the central nervous system was not very clear. This study intends to use rats with MCAO model as the research object, by using the 7.0 T fMRI to observe the MRI signal changes of cerebral areas when electro-acupuncture at "Quchi (LI 11)", "Zusanli(ST 36)",simultaneously combined with transmission electron microscope to observe the morphological changes of synapses, from the view point of whole, function, dynamic to discuss the central nervous system mechanism of electro-acupuncture at "Quchi ", "Zusanli" improving dyskinesia after stroke, at the same time provide the visibility experimental basis, and provide theoretical basis for clinical clinical application.