微纳流体系统在机械、微电子、生物医学等领域已取得广泛应用，但微纳流体传热性能的机理研究仍不完善，这制约了微纳流体系统的进一步发展与应用。本项目将采用理论分析、分子动力学仿真及AFM实验相结合的方法，揭示固液界面表面电荷、边界滑移与温度之间的耦合关系，进而揭示表面电荷与边界滑移对微纳流体传热性能的影响规律及机理。首先理论分析表面电荷与边界滑移间的耦合关系及温度对二者的影响，建立表面电荷、边界滑移与温度间耦合关系的数学模型，并进行实验验证；其次以微管道压力驱动流为例，将表面电荷、边界滑移与温度间耦合关系的数学模型引入Navier-Stokes方程和能量方程，建立微管道内流体速度场与温度场的理论模型，揭示表面电荷与边界滑移对微纳流体温度分布及努塞尔数的影响规律，并分析其机理；最后探究微纳流体对流换热性能的优化控制方法。本项目将完善微纳流体传热性能物理机理的研究，并促进微纳流体系统的应用与发展。

Although the micro/nanofluidic systems have wide applications in mechanical, microelectronic and biomedical fields, the deep studies on the physical mechanisms of heat transfer of micro/nano flow is still needed, and this has blocked the further application and development of the micro/nanofluidic systems. Based on theoretical analysis, molecular dynamics and atomic force microscopy experiments, the present research is carried out to reveal the coupling of surface charge and boundary slip at solid-liquid interface and the temperature, and then reveal the effect of surface charge and boundary slip on the heat transfer of the micro/nano flow. Firstly, both the coupling of the surface charge and boundary slip and the effect of temperature on these two interfacial phenomenon are theoretically analyzed, and the mathematical models of the coupling of surface charge, slip and temperature are established and experimentally verified. Secondly, taking the pressure-driven flow in a microchannel as an example, the coupling of surface charge, slip and temperature is introduced into the Navier-Stokes equation and energy equation, and a theoretical model is established to study the velocity field and temperature field of the fluid flow in the microchannel, and analyze the effect of surface charge and boundary slip on the temperature distribution and Nusselt number of the micro/nano flow. Finally, methods are explored to optimize and control the heat convection at micro/nano scale. The study can both improve the physical mechanisms of heat transfer of fluid flow at micro/nano scale and promote the application and development of micro/nanofluidic systems.