现有采用活性污泥法的城市污水厂对雌激素的去除效率较低，导致雌激素残留随出水排出，存在很高的环境风险。为了强化活性污泥对雌激素的去除效果，需要对雌激素的迁移去除机制进行深入的解析。在雌激素去除过程中，活性污泥胞外聚合物(Extracellular polymeric substances, EPS)可以与之发生动态的结合/解离作用，直接影响其在活性污泥系统中的迁移和去除行为。然而目前针对EPS与雌激素的相互作用仍然缺乏系统性的研究工作。本项目拟基于表面等离子共振与等温滴定量热技术的结合，建立表征活性污泥EPS与雌激素相互作用的动力学和热力学分析方法，探索EPS结合/解离雌激素的动态作用机制，考察EPS和雌激素相互作用的主控因素，阐明EPS在雌激素迁移和去除过程中所起的作用。本研究为优选生物处理工艺，强化EPS对雌激素的结合功能，提高雌激素在活性污泥体系的去除效率提供理论依据和新的思路。

The removal efficiency of estrogens are relatively lower in most wastewater treatment plants, leading to the presence of estrogen residues in effluents and a high environmental risk. In order to improve the estrogens removal efficiency, the removal and migration mechanism of estrogens in activated sludge system should be explored thoroughly. During the process of estrogens removal, extracellular polymeric substances (EPS) of activated sludge can interact with estrogens by association/disassociation, influencing the migration and removal of estrogens in wastewater treatment plants directly. However, systematic research on the crucial roles of EPS in the removal of estrogens are still lacked. In this proposal, combining surface plasmon resonance (SPR) with isothermal titration calorimetry (ITC) technology, the kinetics and thermodynamics of interactions between EPS and estrogens will be characterized and the influencing factors will also be discovered. The interaction mechanism will be discussed in depth, and the contributions of EPS to the migration and removal of estrogens during wastewater treatment process will also be explored. Theoretical basis and new solutions were proposed for improving the removal efficiency of estrogens in activated sludge system, by optimizing biological treatment process and strengthening the binding function of EPS to estrogens.