平滑追随眼动把运动中的物体影像投射到中央凹，以此获得清晰影像。平滑追随眼动的异常是精神分裂症病人中最常见的缺陷之一，因此平滑追随眼动研究有助于精神分裂症机制的了解。研究已表明平滑追随眼动中注意的参与，但其神经机制不是很清楚。因此，本项目拟采用经颅磁刺激（TMS）技术，探讨人类平滑追随眼动中注意分配的神经机制。针对此问题，本项目将TMS刺激平滑追随眼动的核心皮层脑区（MT/MST、FEF、SEF）和注意相关脑区（PPC），设计一系列平滑追随眼动和注意的双任务实验，通过分析实施于各脑区的TMS刺激对平滑追随眼动和注意任务的影响，探讨1）平滑追随眼动中注意在空间分配的神经机制、2）注意负荷对平滑追随眼动的影响的神经机制，以及3）整合运动信息时，全局和局部上的注意分配的神经机制。进一步，本项目将通过比较TMS刺激对不同脑区时的不同影响，建立平滑追随眼动中注意分配的神经机制的模型。

Smooth pursuit is a type of eye movement to foveate moving object in order to obtain clear retinal image. Deficit of smooth pursuit is repeatedly observed in Schizophrenia patients, so it is valuable to study smooth pursuit for understanding the mechanism of Schizophrenia. Many studies showed that attention is involved in smooth pursuit, but its neural mechanism is not clear yet. Therefore, the current project aims to investigate the neural mechanism of attention allocation during smooth pursuit using transcranial magnetic stimulation (TMS) technology. The current project would pick smooth pursuit-related and attention-related brain areas such as middle temporal/medial superior temporal area (MT/MST), frontal eye field (FEF), supplementary eye field (SEF), and posterior parietal cortex (PPC) as interested areas for the TMS stimulation. Then, we would design a series of dual-task experiments with smooth pursuit and attention tasks and measure the performance of these tasks with and without TMS stimulation. By comparing the effect of TMS stimulation, we would explore the role of interested brain areas in 1) the distribution of spatial attention during smooth pursuit; 2) the effect of attentional load on smooth pursuit; 3) the distribution of attention between global and local motion signals. Furthermore，the current project would model the neural system of attention allocation during smooth pursuit using these interested brain areas as nodes.