核盘菌（Sclerotinia sclerotiorum ）引致的油菜菌核病是世界油菜生产中的最重要病害之一，尚未发现好的抗病材料，有待于对油菜-核盘菌互作分子机制进行深入研究。我们前期研究结果表明2个油菜Qa-SNARE蛋白SYP122强烈受到核盘菌侵染的诱导，说明它具有调控油菜对抗核盘菌侵染的功能。在此基础上，本项目拟详细分析油菜中调控菌核病抗性的Qa-SNARE蛋白家族成员的表达动态、在油菜-核盘菌互作中的作用、所涉及的信号途径以及蛋白互作网络， 从而揭示Qa-SNARE蛋白对植物-核盘菌互作的调控机制，并为抗病育种寻找新资源，为科学防控菌核病提供科学依据。

Sclerotinia stem rot disease of rapeseed, caused by Sclerotinia sclerotiorum, is a worldwide disease around the world. The disease could cause destructive yield loss. However, there is no highly resistant material found until now. This needs the further dissection of the molecular interaction mechanism of plant and S. sclerotiorum. We found two SYP122s，belong to Qa-SNARE family of Brassica napus were highly induced by the infection of S. sclerotiorum, indicating that these two proteins can regulate the defense to S. Sclerotiorum.Therefore,in this project, we propose to analyze the expression profiles, the role in B. napus-S. sclerotiorum interaction,the signalling pathway of the Qa-SNARE proteins and their networks of protein-protein interaction in B. napus. The results will reveal the molecular mechanism of Qa-SNAREs in regualting plant-S. sclerotiorum interaction and provide a theoretical basis for improving plant resistance to S. sclerotiorum, breeding and utilization of resistance varieties.