MeO/OH-PBDEs具有危害人体健康的神经发育毒性、雌激素活性和生殖毒性等。它不仅是外源性PBDE的生物代谢产物，而且由于在甲藻等赤潮藻体内能内源性自然合成而存在于海洋生态系统的各营养级生物中，因此直接加剧赤潮的海洋生态风险。基于粤港澳大湾区近海海域是赤潮多发区，但有关MeO/OH-PBDEs的研究尚少，本申请拟在近海海域采集水相、沉积相、藻类和浮游动物样品，研究MeO/OH-PBDEs在不同介质中的时空分布特征及迁移转化规律；通过鉴定藻类MeO/OH-PBDEs的合成量，探讨MeO/OH-PBDEs在赤潮生消过程的合成和传递规律；通过藻类-浮游动物二元食物链培养，揭示MeO/OH-PBDEs在赤潮生消过程的合成和传递机制，从而明晰MeO/OH-PBDEs在粤港澳大湾区近海海域的环境归趋，为评估MeO/OH-PBDE的海洋生态风险提供科学依据，对建设“宜居宜业宜游”大湾区至关重要。

MeO/OH-PBDEs have neurodevelopmental toxicity, estrogenic activity, antiandrogenic activity, and antiglucocorticoid activity and reproductive toxicity, and are known to exist in various trophic organisms of marine ecosystem. MeO/OH-PBDEs are not only exogenous metabolites of PBDEs, but also endogenous synthesized by red tide algae such as dinoflagellates.This will directly aggravate the marine ecological risk of red tide. The Guangdong-Hong Kong-Macao Greater Bay coastal waters area are prone to algal bloom. Research about the relation of red tide and MeO/OH-PBDEs were were rarely in this area. Therefore, sea water, sedimentary, algae and zooplankton samples were collected in this area. The concentrations of MeO/OH-PBDEs in the samples were analyzed to study the spatial and temporal difference of water, sedimentary and biofacies. MeO/OH-PBDEs was analyzed by the purification of red tide dominant algae to further reveal the synthesis and transmission of MeO/OH-PBDEs in the of red tide. Algae-plankton binary food chain was used to reveal the synthesis and transmission mechanism of MeO/OH-PBDEs. This study will provide a scientific basis for the assessment of MeO/OH-PBDE exposure to marine ecological. Revealing the potential ecological risks of MeO/OH-PBDEs is vital importance to build a “good for living, working and leisure city” of the Great Bay area.