血糖控制不良是造成糖尿病疾病负担的根源，自我管理对优化患者血糖控制有重要意义。既往国内外自我管理干预常使患者处于被动依从、被动改变的地位；移动健康是推动干预模式转型发展的重要契机，但现有基于移动健康的干预多因授权照护路径模糊、医护患交互不充分而导致患者参与度欠佳、干预有效性及持续性不理想。本研究拟从血糖控制不良糖尿病患者的健康照护需求出发，构建基于授权过程理论的移动健康管理模式，研发集“疾病管理、碎片学习与实时反馈、同伴支持、护患交互和多学科合作”为一体的移动平台，重点促进患者的知情决策和主动参与。进而，开展随机对照实验，采用广义估计方程评估所构建模式对患者血糖控制、自我管理行为等的影响，并进行成本效用分析揭示干预的经济学效益。最后，通过量性—质性顺序设计、并行三角互证策略阐明干预机制。本研究将探索糖尿病患者自我管理的新路径，为推广实施基于授权的移动健康管理模式提供有力科学依据和数据支撑。

Poor glycemic control contributes significantly to the burden of diabetes and self-management are among the key strategies to optimize patients’ glycemic control. Previous self-management interventions often emphasize passive compliance and passive change, and therefore interventions effectiveness and its long-term effect remains suboptimal. The emergence of mHealth provides an important opportunity to promote the development and implementation of innovative intervention models. However, lack of empowerment care pathways and inadequate physician-nurse-patient interactions limit patients’ autonomy and engagement in current mHealth-based interventions. The effectiveness of mHealth-based interventions is therefore compromised. This project aims to investigate the needs of patients with poorly controlled diabetes and then develop an Empowerment Process Model (EPM)-Based Self-management Interventions for patients with diabetes using mHealth platform, which integrates “disease management resources, fragment learning and real-time feedback, peer support, nurse-patient interaction and multi-disciplinary collaboration”. The vision of this EPM-based self-management interventions via mHealth is to promote informed decision-making and patients ’active participation. Then, a randomized controlled trial will be conducted and generalized estimating equation models will be used to evaluate the effectiveness of the EPM-based self-management model on patients' glycemic control and self-management behaviors of patients with poorly controlled diabetes. A cost-utility analysis will also be performed to reflect intervention benefits from an economic perspective. Finally, the intervention mechanism will be elaborated through QUAN-qual sequential design with concurrent triangulation strategy. This project will shed lights on the development of innovative strategies to promote patients’ self-management and provide scientific evidence for the implementation and dissemination of the mHealth EPM-based model.