本项目属于“共性导向、交叉融通”特色研究，旨在面向水泥基结构材料延寿需求，交叉生物医学工程前沿进展，研究发展一种全新的模拟动物骨骼损伤修复过程的水泥基自修复材料。以“是否可以利用水泥中的钙质结合磷酸盐修复组分原位生长羟基磷灰石实现水泥基材料的自修复”为科学问题，提出微血管网络缓释生长组分原位调控形成羟基磷灰石、利用其胶结能力及时填充封闭混凝土裂缝、实现水泥基材料的自发同寿命高效自修复的新思路。运用X射线CT等先进技术手段，开展微血管网络超分子封装磷酸盐技术、羟基磷灰石原位生成技术、骨仿生水泥混凝土材料自修复技术研究，揭示材料反应机理，提出羟基磷灰石分子结构调控方法，论证材料自修复效率和长期性能，建立全新的智能超分子驱动骨仿生自修复水泥基材料理论体系。项目依托硅酸盐建筑材料国家重点实验室、材料复合新技术国家重点实验室实施，具有较好人员基础、实验条件基础和前期研究基础。

This proposal is based on the concept of “Common orientation, interdisciplinary driving”, taking use of recent advances in biomedical engineering and aiming at the demand of service life extension of cementitious materials. The main objective of the project is to develop a bone-mimic self-healing cementitious materials with the scientific hypothesis “developing a self-healing cementitious materials based on in-situ hydroxyapatite formation with calcium element from cement hydration and phosphates from healing agent”. Formation of hydroxyapatite is the main driving mechanism for the self-healing process with controlled release of functional elements from the supramolecular microvascular network, providing binding capabilities and sealing the cracking, via which a novel spontaneous self-healing technique with high efficiency and comparable service life is developed. The main research activities take use of advanced analytical techniques (e.g. X-Ray CT) and involve packaging phosphates in supramolecular microvascular network material, in-site forming hydroxyapatite, and developing the techniques of bone-mimic self-healing cementitious materials. The major knowledge contributions include the reaction mechanisms of materials, methods for tuning the structure of hydroxyapatite, long-term performance of the self-healing materials, and the novel theoretical systems of bone-mimic self-healing cementitious materials. The research will be accomplished in two state key laboratories in the field of materials science with solid personal and facility foundations.