硫代水杨酸可以对环境中的水体和大气造成污染，对硫代水杨酸进行高灵敏度的快速检测、富集/分离对保护人类生存环境和大众健康具有重要意义。本课题拟分别合成FePt@Ag和FePt@Ag@SiO2核壳复合结构体系，并以其作为SERS基底，对硫代水杨酸进行SERS检测和富集/分离。通过调控FePt结构，获得具有不同磁性的FePt磁性核，建立外加磁场与SERS信号的关系，揭示SERS物理和化学增强机理；将FePt@Ag和FePt@Ag@SiO2表面获得的硫代水杨酸SERS信号进行对比，研究硫代水杨酸在不同SERS基底表面的吸附行为和SERS信号产生机制。该课题拓展了磁性纳米颗粒的应用领域，实现了物理、化学、材料等多学科领域的交叉，建立了一种高灵敏、快速检测硫代水杨酸的新方法。

Thiosalicylic acid (TSA) can pollute the water and air in the environment. To detect, gather and separate sensitively and quickly the TSA is significant to protect the human survival environment and public health. We will synthesize the FePt@Ag and FePt@Ag@SiO2 core-shell composite substrates and detect, gather and separate the TSA, respectively. By regulating the FePt structure, we will obtain the FePt cores with the different magnetic properties. We will construct the relation between the applied magnetic field and the surface-enhanced Raman spectrum (SERS) intensity and uncover the SERS physical and chemical enhanced mechanism. By contrasting the SERS signals obtained on the substrate surface of the FePt@Ag and FePt@Ag@SiO2, we will study the absorption behaviors and the generation mechanism of signals on the SERS substrate surface. This project expands the application fields of the magnetic nanoparticles, realizes the multi-disciplinary crossing including the Physics, Chemistry and Materials science, establishes a highly sensitive and rapid detection method for TSA.