薏苡是传统药食兼用经济作物，具有极高的营养价值和药用价值。我国薏苡主栽区生产品种单一，开发特异薏苡分子标记是挖掘优良农艺性状的一种十分有效的途径。本项目借助于高通量测序技术开发大量SSR和SNP标记，构建了一张薏苡高密度遗传连锁图谱；在连续多年表型性状测定的基础上，对薏苡千粒重、支链淀粉、蛋白质含量、粒型及药用有效成分等性状进行了QTL分析，从而揭示薏苡重要农艺性状基因位点在分子遗传图谱中的分布特点和规律；并探讨了薏苡杂交亲本分子标记遗传距离与子代生长性状之间的关系。相关研究结果为在分子水平开展薏苡遗传改良工作奠定基础，对深刻理解薏苡重要品质性状的遗传机制具有重要意义。

Coix lacryma jobi L. is a traditional economic crop as drug and food with high nutritional and medicinal value. Cultivation of new varieties of Coix lacryma jobi L. with high yield and quality has become the major target as its genetic background was narrow, the species variety was single in the main plant area. For promoting the development of Coix lacryma jobi L. industry, specific molecular markers and mining excellent agronomic traits could be used as an effective way. In this project high throughput sequencing has been use for building high density linkage map of Coix lacryma jobi L. through SSR and SNP marker. Using the genetic linkage map and phenotypic data measured over many consecutive years, quantitative trait loci (QTL) analysis was conducted for thousand grain weight, amylopection contents, protein contents, grain type traits and secondary metabolite contents. It can be used for studying the QTL of important quanlity traits distribution character and regulation in molecular genetic maps of Coix lacryma jobi L.. Relationship between progeny growth performance and molecular marker-based genetic distances was evaluated. This provides a basis for understanding the genetic architecture of these important quanlity traits and for molecular Coix lacryma jobi L. breeding.