环糊精接枝超支化聚硅氧烷制备及其在环境水样农药残留分析中的应用研究

固相微萃取是一种简便、快速、有效的样品前处理技术，适用于环境样品中微量、痕量污染物的吸附、富集和分离，固相吸附材料的选择对保证该技术的萃取效果起着非常重要的作用。本项目根据超支化聚合物拥有分子内部空穴及丰富的可修饰官能团的结构特点以及环糊精的分子识别、生物相容性、易降解、无污染等特性，设计合成新型环糊精接枝超支化聚硅氧烷，并将其作为固相微萃取技术中的固相吸附材料，采用不同萃取模式研究它们对环境水样中特定类型农药残留的选择性萃取，考察影响环糊精接枝超支化聚硅氧烷萃取效率的因素，优化萃取条件，结合现代仪器分析方法，建立基于环糊精接枝超支化聚硅氧烷的固相微萃取技术。该研究成果能够提高固相微萃取技术对于目标物的萃取富集效能、降低基体的干扰，对环境样品痕量/超痕量农药残留分析监测有重要应用价值。同时还能拓展超支化聚合物在环境科学领域应用，促进超分子化学、环境分析和功能材料等化学分支学科的交叉融合。

Solid-phase microextraction (SPME) is a simple, rapid and efficient sample pretreatment method for the analysis of trace pollutants in environmental samples. The selection of sorbent is very important in SPME In this project, a series of functionalized cyclodextrin hyperbranched polysiloxysilane (CD-HPS) will be synthesized based on the unique structures and properties of hyperbranched polymer and cyclodextrin, such as intramolecular cavities and abundant functional groups of hyperbranched polymer, and molecular recognition, biocompatibility, degradation, non-pollution properties of cyclodextrin. The resulting CD-HPS will be utilized as novel sorbent in the SPME process of pesticide residues in environmental water samples. With the combination of modern analytical instruments, the extraction efficiency and enrichment ability of the new CD-HPS sorbent for the pesticide residues in environmental water samples will be studied in depth. In addition, the extraction conditions will be optimized to increase the extraction efficiency and reduce the time of extraction process. Finally, the novel, fast, efficient and environmental benign CD-HPS-SPME method will be established for the analysis of typical pesticide residues in real water samples. This research will be of vital application value for analyzing and monitoring pesticides residues at trace or ultra-trace concentration level in environmental water samples, and will expand the application area of hyperbranched polymer in the field of environmental science research and promote the cross integration of sub-disciplines of chemistry, such as supramolecular chemistry, environmental analysis and functional materials etc.