香樟木材被公认具有很强的耐腐性能，越来越多的研究显示，香樟不同部位提取物具有抑菌、抗炎和驱虫等多种功效，但是目前关于香樟提取物对木材腐朽菌的抑制作用机制还未见报道。我们前期的耐腐和毒力试验研究结果显示，香樟木质部三氯甲烷提取物与甲醇提取物分别对彩绒革盖菌（白腐菌）和密粘褶菌（褐腐菌）的抑制效果明显。为此，本课题针对香樟木质部提取物在木材防腐中的作用机制展开深入研究，一是从细胞膜渗透、呼吸代谢、纤维素酶活性方面阐明香樟木质部提取物对木材腐朽菌的生理生化机制；二是通过蛋白质双向电泳及质谱技术相结合，解析提取物对木材腐朽菌的相关蛋白质表达以及信号通路的影响，从分子水平揭示香樟木材次生代谢产物抑制木材腐朽菌的机制。本研究对全面认识香樟提取物的抑菌防腐机制及其今后用于木材防腐剂的研制与开发具有重要意义。

The wood of Cinnamomum camphora has good decay resistance performance. More and more studies have shown that the extractives of C. camphora has antibacterial, anti-inflammatory, desinsectization and other effects. But at present, there is no report on the antifungal mechanism of C. camphora extractives against wood-rotting fungi. The results of our previous studies on the C. camphora xylem showed that had significant antifungal effects of Coriolus versicolor (white rot fungi) and Gloeophyllum trabeum (brown rot fungi), respectively. Therefore, we will study the antifungal mechanism and wood preservatives of C. camphora xylem extractives from two aspects: firstly, we will illuminate the physiological and biochemical mechanisms of C. camphora xylem extractives against wood-rotting fungi from the aspects of cell membrane permeability, respiratory metabolism and cellulase activity; Secondly, we will reveal the antifungal mechanism of the secondary metabolites of C. camphora xylem extractives through two-dimensional electrophoresis and mass spectrometry. This study has great significance for comprehensively understanding of the C. camphora xylem extractives’ antifungal mechanism and application in the research and development of wood preservatives.