随着质子重离子在肿瘤放疗临床中的推广应用, 相关高能荷电粒子在靶组织和非靶组织中的吸收剂量以及治疗室内的感生放射性的精确测量与评估问题已成为了辐射测量与剂量学领域亟需解决的重点与难点问题之一。本项目拟基于固体核径迹探测技术，先可借鉴CT图像重建算法并利用旋转光源技术对径迹进行全角度成像以实现其三维结构的微米级重建，再利用最大似然估计方法对蚀刻过程进行逆向反演以获取荷电粒子输运路径“潜径迹”的三维信息，最终确立可同时测量粒子注量和能量的新技术；在该技术的基础上，开发设计基于固体核径迹探测器CR-39的组合来开展放射治疗中质子重离子的注量、能量和LET测量的新方法，并实现对中子等次级粒子的全能谱测量。本项目的结果不仅可为质子重离子放疗的剂量精确评估、质量控制和辐射防护提供亟需的技术手段，也将为提升固体核径迹探测技术的性能和探测，拓展其在医学物理、航空航天等领域中的应用起到有力的推动作用。

With the application of the proton or heavy-ion radiotherapy, to evaluate the absorbed dose at the target tissue as well as the surrounding radiation field becomes critical issues in the field of radiation dosimetry. Based on solid state nuclear track detector (SSNTD), this study intends to develop a new track counting system with rotating light source which could reconstruct the 3D structures of etched tracks within micron precision. In order to extend its ability of the detector, the transport path of charged particles, called "latent track", would be reversely estimated by using EM method. The method to simultaneously measure both the flux and the energy of insert heavy ions as well as the technique for monitoring neutron energy spectrum would be established based on the 3D reconstruction and the latent track estimation. The new method is planned to accurate evaluate the dose distribution at the target and non-target area in heavy-ion radiotherapy and to measure mixing radiation field in the clinic for the radiotherapy. The result in this study provide a new method for dosimetry studies related to proton or heavy-ion radiotherapy and will effectively improve the performance of the SSNTDs which could expand its application in medical physics, aerospace radiation and neutron measurement.