我们创新性地将有机合成化学中的自由基串联反应和高分子化学中的自由基聚合反应相结合，提出一种全新的基于自由基串联的聚合反应/可控聚合反应（Radical Cascade Mediated Controlled Polymerization，RCMCP）。在该项目中，基于1，5-氢原子自由基转移机理为基础的自由基串联聚合反应作为一个模型，以此证明这类全新自由基聚合方向的可行性和展现这个概念的普适性。我们计划设计并合成相关新型单体，使用模型反应获得自由基基元反应的速率常数，进而优化单体结构达到高效的串联聚合。使用这一新类型的反应可以合成带有序列控制的单体，进而合成序列可控聚合物，与此同时可以合成一系列可调节接枝密度和位置的刷子型聚合物。

The free radical tandem reaction in organic synthetic chemistry is combined with the free radical polymerization in polymer chemistry, and propose a novel free radical polymerization method based on tandem free radical transformations (Radical Cascade Mediated Polymerization, RCMP). In this project, radical cascade mediated polymerization based on 1,5-hydrogen atom transfer shows the proof of concept. We plan to design and synthesize new types of monomers, and investigate the model reaction to have the basic rate constants of various related radical transformations. The monomer will be further modified to improve the efficiency of radical cascade mediated polymerization. The monomers that contains sequence-coded units will be synthesized and to provide a sequence-controlled polymer using this new polymerization methodology. The brush polymer with different grafting density and position also could be synthesized.