共轭多烯片段由于其独特的结构，在有机合成化学中一直都是研究的对象。本研究计划拟采用廉价金属铁作为催化剂，从三个部分进行研究：利用C-H键官能团化模式，实现铁催化下双烯烃氧化偶联反应；利用 Fe-R 等关键金属中间体，对烯烃和炔烃进行选择性的串联偶联反应; 利用还原偶联的策略，对烯烃衍生物进行选择性的交叉偶联反应；从而为合成共轭多烯提供重要的方法。总之我们希望通过本研究计划，发展更为简单、高效、立体专一而且取代基灵活多样性的方法来合成共轭多烯衍生物。

Conjugated polyenes are synthetically useful materials in academia and industry. The selective functionalization of polyenes for access to a diversity of molecules has become an attractive and challenging topic in organic synthesis. This research plan will focus on developing simple and efficient methods for synthesis of conjugated polyenes via iron catalyzed ross-coupling reactions. We propose three different strategies to prepare the conjugated polyenes. Direct oxidative cross-coupling of simple alkenes to form polyenes would be the most attractive strategy; An alternative strategy would be the domino reactions of alkenes and alkynes via a vital intermediate Fe-R or iron hydride species; In addition, we also would present the reductive cross-coupling reactions using ketones derivatives and alkene halides as coupling partners. In a word, we would like to present the simple and efficient methods for the synthesis of stereospecificity and controlled-diverse substituted group conjugated polyenes via iron catalysis.