橡胶由于其特殊的性能广泛用于与食品接触的婴幼儿用品中。由于复杂的配方成分及加工过程，使其在与食品接触时，其中潜在的化学物质迁移污染婴儿食品，或直接由婴幼儿的吮吸进入体内，从而对这一特殊生理时期的消费群体的健康带来严重危害。本课题以婴幼儿食品接触橡胶（乳胶、硅胶和热塑性弹性体）制品为研究对象，首先建立婴幼儿食品接触橡胶制品中潜在迁移物的测试筛选体系,利用多种分析方法如色质联用技术等，对制品中不同性质的潜在迁移物进行检测分析，得到其丰富的谱峰信息；其次建立潜在迁移物的数据信息库，根据谱峰的结构信息等进行分类及定性、定量分析，并对具有潜在毒理性的物质进行分类筛选；最后对具有潜在毒理性的迁移物进行迁移规律研究，以提出避免或限制向食品中发生有害迁移的方法。目前国内外尚未见婴幼儿食品接触橡胶制品中潜在迁移物的系统性研究。

Rubber materials are widely used in infant food contact rubber products because of its special performance. Due to the complicated ingredients and machining process of rubber products, the potential migrants in them are possible to contaminate baby food or directly be sucked into body, which is harmful to the health of the consumer groups in the special physiological period. The infant food contact rubber products including latex, silicon and thermoplastic elastomer (TPE) products are taken as the objects of this research. Firstly, the test screening system of potential migrants in infant food contact rubber products is established using a variety of analytical methods to detect the potential migrants possessing different properties and obtain the abundant peaks information. Secondly, the data information base of potential migrants is set up, which includes the classification according to the structure information of the peaks, the qualitative and quantitative analysis, and the screening of the potential toxicological substances. Finally, the study of the migration rules of the potential toxicological substances is carried on, in order to propose the effective methods to avoid or limit the harmful migration into food. The systemic study of the potential migrants in the infant food contact rubber products has not been reported.