固体样品直接元素定量分析中寻找匹配的固体标准品不仅耗时耗力，还会消耗大量的资金，尤其是针对未知样品。气体辅助激光电离质谱（BGA-LI-MS）分析技术是在氦气氛围内采用高功率密度激光对样品进行一步溅射和电离，通过待测元素离子流除以总离子流可以简便地获得每种元素的摩尔浓度，可实现无需标准样品直接对固体样品中的元素组成进行半定量分析。本项目旨在研发与BGA-LI-MS配套的新型进样系统和离子传输系统，减小离子源中杂质气体的干扰，提高离子传输效率，从而进一步提高检测准确度，降低各元素检出限至ppb级，实现高准确、高灵敏地对固体样品中元素组成的无标样半定量分析；同时评估该仪器对于不同基体固体样品的分析性能，探索离子源中可能存在的干扰来源及其对分析结果的影响，并研究基体对无标样半定量分析的影响。

In the direct element quantitative analysis of solid samples, it is difficult to find a series of matched solid standard samples, especially for unknown samples. With the buffer-gas-assisted laser ionization mass spectrometry (BGA-LI-MS) analysis technique, the sample is sputtered and ionized with high power density laser in helium atmosphere, and the molar concentration of each element can be obtained simply by dividing the measured ion flow of elements with the total ion flow. The main work of this project is to develop a new type sample injection system and ion transport system of BGA-LI-MS to reduce the interference in the ion source and increase the ion transport efficiency, and further to improve the detection accuracy and lower the detection limit of each element, ultimately the semi-quantitative analysis of element composition in solid samples is realized without the need of standard samples. We will also evaluate the analytical performance of the instrument for solid samples with different matrices to explore possible sources of interference in the ion source and their impact on the analytical results. And also, the effect of the matrix on standardless semi-quantitative analysis would be studied.