新疆南疆马鹿资源具有独特性、地域性、稀有性的特征。近年新疆马鹿腹泻严重影响养鹿业发展。由于新疆马鹿疫病研究相对较少，缺乏马鹿腹泻病原系统性研究和马鹿与牛羊共感染疫病研究，流行病学调查的缺乏，以及存在未分类病原，致使马鹿疫病防控困难，难以净化。. 以既往病史、国内外文献、专家建议为参考，现场调查、临床诊断、病理学观察作初步诊断，结合前期马鹿腹泻、牛腹泻研究基础，依据流行病学原理，以宏基因组学方法确定新疆南疆马鹿腹泻病原（包括未分类病原）种类，在此底数基础上，开展新疆南疆马鹿腹泻疫病的流行病学调查、病原分子生物学特性研究，掌握马鹿腹泻病原感染情况、分子流行病学特征以及病原分子遗传演化规律，对马鹿腹泻疫病进行溯源、疫苗选择有重要作用；另一方面，对牛羊疫病传入养鹿场的风险因素进行分析，为马鹿疫病防控提供重要的理论依据，对疫病防控、净化、减少人兽共患病感染、保护我国稀有动物资源具有非常重要的意义

Red deer is one of China's most prized species with uniqueness, regional and rarity in Southern Xinjiang. The disease of red deer diarrhea seriously affects the development of red deer in Xinjiang. It is difficult to prevent and control for lacking of systemic study and epidemiological investigation of red deer diarrhea. There are even unclassified pathogen in red deer’s diseases..The program will be guided by past medical history, home and abroad reference, specialist’s advice. Metagenomics will be used for identification of red deer diarrhea in southern Xinjiang based on early research of red deer and cattle diarrhea with field survey, clinical diagnosis, pathology observation. We will do epidemiological investigation, molecular characteristic analysis according to result of metagenomics. It is import for us to trace to the source of red deer diarrhea, election of vaccine. On the other hand, we analyze risk factor of epidemic disease of cattle and sheep spreading to red deer. It will help us to get reference of prevention and control of red deer disease. It is vital significance for protection of red deer, control of disease, reduce of zoonosis infection.