以过程工业中换热网络设计为考察对象，将其划分为网络设计和设备设计两个过程进行研究。根据二元整型变量的组合方式提出网络结构的枚举方法，剖析最小传热温差对公用工程用量及换热面积的影响机理，探究物流匹配和热量传递约束的内在关联，总结能耗和设备因素在网络优化中的协同作用规律，建立网络设计的线性数学模型，应用黄金分割、多项式插值、三叉搜索树及分支定界等算法开发网络设计的全局优化算法。通过实验测试物流组分，模拟流体流动和传热性能参数，揭示设备尺寸变量的离散特性，归纳流体流动和热量传递约束的线性化原理，建立管壳式换热器详细设计的线性数学模型。在此基础上综合所建立的数学模型，解析网络设计和设备设计的协调优化机制，开发二者同步设计的全局优化算法。目标在于建立换热网络设计的新模型和优化理论，解决建模和求解方面存在的难题，并应用到实际工业中降低企业能耗，提高经济效益，为节能减排提供科学依据和新途径。

Heat exchanger networks design is studied in this work, which includes network design and detailed heat exchanger design. An enumeration method is proposed to obtain different network structures according the combinations of binary variables. The effects of the minimum heat transfer temperature difference on utility consumption and heat exchanger area is analyzed. The constraints for stream matches and heat recovery are studied. The synergy between energy consumption and equipment factors are concluded. Linear mathematical models for network design are constructed which together with golden search, ternary search, polynomial interpolation and branch and bound methods are applied to develop global optimization algorithms. Stream components are tested through chemical experiment and the hydraulic and thermal parameters are simulated to analyze the discrete nature of heat exchanger size variables. The linearization principles for the constraints of heat transfer and stream flow are proposed. Thus, linear mathematical model for shell and tube heat exchanger design is developed. Based on these linear models, the network and equipment designs are simultaneously considered. The optimization algorithms for heat exchanger networks design with detailed heat exchanger design are developed. The main purpose is to propose new mathematical models and global optimization algorithms for heat exchanger networks design to solve the modeling and computational problems. The proposed models and algorithms provide new scientific theories and methods to energy conservation and emission reduction in process industry.