柔性可穿戴传感-激励智能医疗器件具有非常诱人的应用前景。基于柔性无机高性能压电薄膜的生物共生自驱动技术日益受到人们的关注。绿色无机改性钛酸钡基薄膜能够媲美铅基材料具有出色的压电性能，但相关柔性压电薄膜器件的研究未见深入报道。本项目以柔性化的改性钛酸钡基压电薄膜为基础，从可延展构筑与变形曲面贴附式压电器件的传感激励性能入手，对基于柔性钛酸钡基压电薄膜的可延展生物共生传感-激励一体化器件进行深入研究。具体内容包括：高压电性能钛酸钡基外延薄膜的准同型相界调控机制及柔性化制备；曲面贴附压电传感器的大变形可延展结构、机电耦合性能、运动传感性能的相互作用机理及其调控机制；基于骨质疏松大鼠模型实现共生压电传感-激励一体化器件的活体性能验证及内在机制分析。本项目旨在揭示可延展无机压电薄膜一体化器件的传感-激励作用机理及其性能控制机制，为新型智能医疗监护系统的开发与应用提供新思路和奠定科学基础。

Flexible wearable sensing-actuating smart medical devices have very attractive application prospects. Self-driving symbiotic devices based on flexible inorganic high-performance piezoelectric thin film has attracted increasing attention. Modified barium titanate-based inorganic thin films can be comparable to lead-based materials with excellent piezoelectric properties, however, there is no in-depth report on the research of flexible barium titanate-based piezoelectric thin film devices. In this project, we conduct in-depth research on the extensible symbiotic sensing-actuating integrated devices based on flexible modified barium titanate-based piezoelectric films, starting with extensible construction and the sensing-actuating performance of piezoelectric devices attached to deformed curved surfaces. The specific contents include regulation mechanism of morphotropic phase boundary and flexible preparation of barium titanate-based epitaxial thin films with high piezoelectric properties; the interaction and regulation mechanism of the large deformation extensible construction, electromechanical coupling performance, motion sensing performance of the piezoelectric sensor attached to the curved surface; in vivo verification and internal mechanism analysis of piezoelectric sensing-actuating integrated symbiotic devices based on osteoporosis rat model. This project aims to reveal the sensing-actuating mechanism and regulation mechanism of the symbiotic devices based on inorganic piezoelectric thin film, bringing a new direction and lay a scientific foundation for the development and application of smart medical monitoring systems.