针对高性能位置灵敏型探测器的要求，研究经亚表面激光加工技术（SSLE）加工的闪烁体（如LYSO、LuAG和GAGG等）的光传输性能，以及激光和闪烁体的相互作用机制和规律，确定和优化激光强度，蚀刻的密度，蚀刻层等SSLE闪烁体加工参数及加工工艺，制作微像素闪烁体阵列。然后结合硅光电倍增管（SiPM）等新型光电器件，设计专用读出电子学，研制空间分辨优于1.0mm、时间分辨优于300ps的新型高分辨率位置灵敏探测器，为PET、SPECT和其他辐射成像系统提供技术基础。

This project firstly focuses on the optical transmissions performances of scintillators such as LYSO, LuAG, and GAGG, which are etched internally using sub-surface laser-engraving processing technique (SSLE). Then according to the requirements of high performance position sensitive detectors, the interaction of laser and scintillators will be researched, and the scintillator processing method will be optimized. The appropriate processing parameters, e.g. the laser intensity, the density of etching, etching layer will be determined, and the scintillator array will be processed. Finally, combined with the photoelectric device of silicon photomultiplier and the special readout electronics, a new position sensitive detector of high spatial resolution (1.0mm) and time resolution (300ps) will be developed. This project could provide the technical basis for PET, SPECT and other radiation imaging system.