糖信号是反映植物体内生理状况和外界环境条件的核心信号系统，调控了包括质体蓝素基因在内的数千个基因的表达，与激素、光、胁迫、防卫和矿质营养信号密切互作，对植物生长发育具有重要的作用。在前期研究中，我们克隆了一个质体蓝素基因表达蔗糖非偶联、且长势矮小、早花的拟南芥sun1突变体，通过转基因互补确认SUN1编码Trichome Birefringence-Like蛋白家族成员TBL37。在此基础上，本申请拟运用分子遗传学、植物生理学、系统生物学等的方法，系统研究SUN1/TBL37基因参与细胞壁多糖乙酰化修饰和该基因调控糖信号转导、生长发育以及对胁迫响应的功能；揭示细胞壁结构变异与糖信号转导、生长发育和胁迫响应之间的关系；寻找并验证既能调控TBL37转录、同时又受SnRK1磷酸化调控的转录因子，阐明一个“SnRK1-转录因子-TBL37”调控途径，以及该途径平衡植物生长和胁迫响应的机制。

In plants, sugar signaling is the core signaling system which reflects the internal physiology situation and the external environment condition, regulating the expression of thousands of genes including the plastocyanin gene. Sugar signaling interacts with the hormone signaling, light signaling, stress signaling, defense signaling and mineral nutrition signaling and plays an critical role in plant growth and development. Based on the cloning of the Arabidopsis sun1 mutant which showed the the sucrose uncoupled regulating of the expression of plastocyanin gene, early flowering and small/dwarf phenotypes, this proposal will systematiclly research the functions on acetylated modification of cell wall polysaccharides, and on influencing plant sugar signal transduction, plant growth and development and biotic/abiotic responses of SUN1/TBL37 gene using the methods of molecular genetics, plant physiology, systems biology etc, and reveal the relationships between the cell wall structure variation and the sugar signal, plant growth and development and stress resistance. By searching the transcription factor which is regulated by SnRK1 and regulates the expression of TBL37 and confirming in vitro and in vivo, we will illustrate a SnRK1-transcription factor-SUN1/TBL37 regulation pathaway, and the mechanism of its coordinating the balance of plant growth and the stress response.