基于技术前端的“科学”的创新正推动社会经济范式的转变，建立以科学为基础的创新生态系统是我国赶超发达国家的重要战略。本项目拟解决的核心问题是：如何因循基于科学的创新生态系统的协同演化规律，构建恰当的科学创新政策体系以提升我国的科技创新能力？以科学的创新为切入点，运用生态演化等理论，采用数据挖掘、实证研究等方法，揭示基于科学的创新生态系统的链状网络结构的特征；构建创新生态系统协同创新驱动模型，分析协同创新的动力及机理；构建知识流动GERT网络模型，分析发达/发展中的科学模式下“科学研究—技术转移—产品开发”纵向协同演化轨道。构建基于科学的创新生态系统与政策环境协同演化模型，分析系统与政策环境的横向协同演化规律，探索各创新种群（高校、科研机构和企业）的最优组合。提出支持科学创新的“政策供给—基于科学的创新能力—政策优化”政策体系和对策，为破解当前我国科技创新困境，提升自主创新能力，提供新的思路。

As science is in the front of technology, science-based innovation is driving the revolution of the socio-economic paradigm, and the establishment of a science-based innovation ecosystem is an important strategy for China to catch up with developed countries. The core problem to be solved in this project is: How to follow the law of synergy evolution of science-based innovation ecosystem and construct an appropriate science innovation policy system to enhance Chinese scientific and technological innovation capability? Taking science-based innovation as the starting point, using ecological evolution and other theories, using data mining and empirical research to reveal the characteristics of the chain-like network structure of science-based innovation ecosystem; Constructing a collaborative innovation drive model for innovative ecosystems and analyzing the dynamics and mechanisms of collaborative innovation; Constructing a knowledge flow GERT network model and analyzing the vertical synergistic evolutionary track of “science research—technology transfer—product development” based on the model under developing/developed science; Constructing a science-based collaborative ecosystem and policy environment collaborative evolution model, analyzing the horizontal synergistic evolution of the system and policy environment, and exploring the optimal combination of innovative populations (universities, research institutions and enterprises). It puts forward the policy system and countermeasures of “policy supply—the ability of science-based innovation—policy optimization” to support science innovation, and to provide new ideas for solving the current scientific and technological innovation dilemma in China and enhancing independent innovation capability.