单一手性配位聚合物在不对称催化、手性识别与分离以及非线性光学等领域具有潜在的应用。由非手性有机配体可控组装单一手性配位聚合物是配位聚合物合成化学的挑战之一。本项目结合手性色谱分离技术和分步组装的策略，为解决这一问题提出新的组装思想，即首先通过螯合的非手性有机配体与金属离子配位合成手性离散配位分子的外消旋混合物，然后通过色谱技术分离得到单一手性的离散配位分子，进而将这些单一手性的配位分子作为前体（金属配体）组装成单一手性配位聚合物并研究它们的结构与组装规律。此外，结合我们的研究结果与研究积累，将把单一手性多孔配位聚合物作为固定相应用于毛细管气相色谱中，通过毛细管气相色谱手段研究手性配位聚合物对手性小分子的识别和分离性能，以此为基础定量阐述配位聚合物结构与色谱分离性能之间的构效关系。

Homochiral coordination polymers (CPs) have various potentail applications on asymmetric catalysis, enantioselective recognition and separation, non-linear optical materials, and so on. However, the controllabe synthesis of homochiral CPs is still a great challenge, especially starting from inexpensive and versatile achiral organic ligands. In the current project, we will propose a new stagety to solve the problem by combination of chromatography chiral seperation and step by step assembly approach. First, starting from achiral chelate organic ligands, racemic mixture of discrete chiral coordination coomplexes will be synthesized and separated into their single enantiomers mainly by HPLC, then the enantiomerically pure discrete coordination complexes will be used as precursors to further assemble homochiral coordination polymers by step by step approach. The structures and assembly mechanism of the constructed homochiral coordination polymers will be investigated thoroughly. Based on our research result, we will focus on the application of homochiral CPs in capillary gas chromatography (CGC). The performance and ability of chiral CPs in recognizing and separating small chiral molecules will be studied via CGC method and the quantitative relationship between structures and chromatography separating properties will be established.