废用综合征（disuse syndrome，DS）是机体长期丧失活动能力而产生的继发病理状态,是康复治疗的重大课题。前期工作中，我们对DS患者进行挛缩干预及改善生活质量（QOL）研究，取得了一定的成效。维吾尔医学（维医）对DS患者康复治疗有一定的理论建树，并有方药治疗为主、理疗为辅的特色方法。故本研究拟采用熏蒸药浴护理等维医特色疗法及微振动、运动训练等西医理疗法，对DS患者进行康复护理干预，通过关节活动度（ROM）、肌力、肌肉深部血流量、肌腱恢复程度及炎症因子水平等多种指标分析，探讨维西医结合疗法对日常生活能力（ADL）和QOL的影响和疗效；制作关节挛缩DS兔模型，模拟临床康复干预措施，对ROM和局部血流量以及关节液、关节囊滑膜和局部肌肉组织进行关键炎症因子指标分析，验证临床观察的疗效机制的动态性和准确度，探讨一种合理可行的DS临床护理和评估方法，并为揭示维西医结合疗法的科学性提供依据。

Disuse syndrome (DS) is a secondary pathological state of the body caused by long-term loss of physical activity, and became the main topic of clinical rehabilitation. Our previous studies showed a relatively good impact of contracture intervention on the quality of life (QOL) of DS patients. Uyghur medicine has a relatively complete interpretation for the rehabilitation treatment of DS patients and developed distinctive methods for treatment of patients with prescriptions, which are combined with auxiliary physiotherapy. In this study, we will treat DS patients for rehabilitation by unique methods of Uyghur medicine such as fumigation bath therapy in combination with physiotherapeutic methods of western medicine such as micro vibration and movement training. The impact and therapeutic effect of this treatment on activities of daily living (ADL) and QOL of DS patients are evaluated by measuring the range of motion (ROM), muscle strength, deep muscle blood flow, and the degree of tendon recovery and the level of serum inflammatory factors. Meanwhile, we will mimic the clinical treatment of DS patients using a rabbit DS model of joint contracture for optimizing clinical treatment methods，and verify the accuracy and dynamics of mechanisms of therapeutic effects in clinical treatment by analysis of ROM and local blood flow and the detection of inflammatory factors in samples of joint fluids, synovial membrane of articular capsules and local muscle tissues. The goal of this study is to establish a rational and feasible method for clinical rehabilitation and evaluation of DS patients, and provide evidence for scientific interpretation of rehabilitation of DS patients by Uyghur medicine in combination with modern medicine.