血液粘度是血液流变学的重要参数，同时也是心脑血管疾病诊断、治疗、预防的重要依据。常规的血液粘度测量需要数毫升样本，且在病理检测过程中，还需要多次采集，增加了被测人的负担，因此微量粘度测量方法的研究十分必要。现有微量粘度测量方法面临着微观尺度下流体热交换和气流压力变化的干扰问题。本项目旨在探索一种全新的基于非对称双通道光纤的微量血液粘度测量方法，借助光纤光栅的光谱测量技术和分布式测量技术，利用光纤的非对称双通道，开展血液进口压力、折射率的同步测量和温度分布、流速分布的同步测量，实现微观尺度下流体热交换和气流压力变化的动态补偿。项目拟设计并搭建非对称双通道光纤微量血液粘度测量平台，研究血液粘度测量的动态补偿算法，在此基础上研究尺寸效应对微量血液粘度测量的影响。项目将深度融合特种光纤传感和微量流体测量领域，有望为微量血液粘度测量提供一种新途径。

Blood viscosity is an important parameter of hemorheology and an important basis for diagnosis, treatment and prevention of cardiovascular and cerebrovascular diseases. Routine blood viscosity measurement requires several milliliters of sample and in the process of pathological detection, it also needs to be collected several times, which increases the burden of the tested person, so it is very necessary to research the measurement method of micro-volume viscosity. The existing micro-volume viscosity measurement methods cannot overcome the disturbance of fluid heat exchange and airflow pressure change on accuracy due to microscale. The purpose of this project is to explore a novel micro-volume blood viscosity measurement method based on asymmetric dual-channel optical fiber. With the usage of the spectral and the distributed measurement technology of fiber Bragg grating, the asymmetric dual-channel of the fiber, the synchronous measurement of blood inlet pressure, refractive index and temperature distribution, flow velocity distribution are carried out to realize the dynamic compensation of fluid heat exchange and airflow pressure changes on accuracy due to microscale. The project plans to design and build a micro-volume blood viscosity measurement platform of asymmetric dual-channel optical fiber, to research the dynamic compensation algorithm of fluid viscosity measurement, and on this basis, to research on the influence of size effect on micro-blood viscosity measurement. The project will deeply integrate the field of special optical fiber sensing and micro-volume fluid measurement, which is expected to provide a new way for micro-volume blood viscosity measurement.