新冠肺炎的迅速蔓延导致大量危重患者需要人工肺辅助治疗，人工肺的治疗费用非常昂贵，其核心耗材膜肺材料更是被国外公司垄断，因此亟需研制新的膜肺替代材料，促进人工肺的国产化。全硅ZSM-58分子筛膜孔径适当、结构稳定，具有较好的CO2/O2扩散选择性，有望成为新的膜肺替代材料。采用常规的水热法合成ZSM-58分子筛膜很难获得厚度超薄的致密膜层，并且会产生大量废碱液排放。为了推动ZSM-58分子筛膜的实际应用，降低膜厚、提高膜的气体交换效率具有重要意义。本项目拟基于高装填密度、低传质阻力的中空纤维载体，采用高效环保的取向晶种辅助无凝胶法制备超薄全硅ZSM-58分子筛膜，通过控制晶种的取向涂覆和晶体的受限生长获得致密薄膜并对膜的结构进行调控；然后研究分子筛膜的气体交换性能，探索膜的气体交换规律和揭示膜的气体扩散机理；最后，研制小型中空纤维膜束器件和建立高效的血液氧合模拟系统，为膜的实际应用奠定基础。

The rapid spread of COVID-19 requires very extensive artificial lung treatment for large number of critically ill patients. The artificial lung treatment costs a lot and its core consumables, membrane lung materials, are monopolized by foreign companies. So, it is urgent to develop new substituted membrane lung materials to promote the localization of artificial lung. All-silica ZSM-58 zeolite membrane that has proper pore size and robust structure provides a good CO2/O2 diffusion selectivity, which might be a promising substituted membrane lung material. It is usually difficult to obtain ultrathin and defect-free ZSM-58 zeolite membrane by the conventional hydrothermal synthesis method. Moreover, a lot of alkali waste are often produced as well. In order to promote the practical application of ZSM-58 zeolite membrane, it is important to reduce the membrane thickness and thereby to improve the gas-exchange efficiency. Based on hollow fiber supports with high packing density and low transfer resistance, this project will be conducted to prepare ultrathin all-silica ZSM-58 zeolite membranes by the high-efficiency and eco-friendly gel-free method using oriented thin zeolite seeds. Ultrathin and defect-free membranes will be achieved by controlling the orientation of seeds and confined growth of crystals and membrane structure will be modulated. After that, the gas-exchange performance of membranes will be studied to explore the gas diffusion rule and mechanism. At last, a demo cell based on hollow fiber zeolite membranes will be fabricated and a high-efficiency blood oxygenation simulation system will be developed. Such achieved results will lay the foundation for practical application of the membrane.