界面聚合是最常规的纳滤膜制备方法，由于其反应速率快，成膜时间短，现有以界面聚合过程调控的方法制备的纳滤膜，其高通量和高选择性往往很难兼顾。由于界面聚合是在支撑层表面发生，其结构和化学组成势必会影响纳滤分离层的结构和性能，为此，本项目拟以调节支撑层表面的化学组成为突破口，以改变界面聚合单体与支撑层表面的相互作用来实现对分离层的调控。具体研究内容包括：制备表面含有不同官能团的超滤膜，实现超滤膜表面化学组成的可控调节；以此为活性支撑层，开展支撑层表面与界面聚合单体间化学反应活性、表面荷电性、表面与水相单体哌嗪之间相互作用力强弱等因素对界面聚合过程和界面聚合所形成的聚酰胺分离层结构、化学组成和分离性能影响的研究，归纳并总结出支撑层表面化学组成对界面聚合过程的影响机理和规律；提出并确立通过调节支撑层表面化学组成来制备高通量和高分离选择性纳滤膜的新策略。

Interfacial polymerization is a common method to prepare nanofiltration membrane. During the interfacial polymerization process, the reaction rate is quite high which results to the very fast and uncontrollable selective layer forming. Recently, the polyamide selective layer with proper structure and chemical composition was constructed by tuning the interfacial polymerization process. However, due to the traditional flux-rejection trade-off, it was difficult to prepare a nanofiltration membrane with both high permeability and high selectivity. As the reaction site of the interfacial polymerization, the formation of polyamide selective layer will be influenced by the surface structure and chemical composition of the substrate. Thus, the aim of this project is to systematically research the influence of the surface chemical composition of the substrate on the interfacial polymerization process, the structure and performance of the polyamide selective layer. In details, a series of ultrafiltration membranes whose surface contained certain functional groups will be designed, prepared and used as the active substrates. The structure and property of the formed polyamide selective layer then will be systematically researched after the interfacial polymerization proceeded on the prepared active substrate. The influence mechanisms of the surface reactivity, the surface charge property and the interaction between the surface and the monomer piperazine of the substrate on the interfacial polymerization process, the structure and performance of the formed polyamide selective layer will be concluded after carefully characterization. According to the findings, the preparation method for nanofiltration membranes with high permeability and high selectivity will finally be established. The findings in this project will provide new insights on the role of substrate on the formation of polyamide rejection layer.