离散金属大环主客体识别体系的建立及其在构筑功能超分子自组装体中的应用

作为超分子化学的一个重要研究领域，基于大环主体的主客分子体识别自始至终都是超分子化学家们研究的热点。设计新的大环主体分子识别体系，以满足主客体化学研究和发展的需求、进一步丰富超分子化学的研究领域，一直以来都是超分子化学家们所努力的一个方向。Pt金属大环是一类利用Pt金属配位键构筑的离散金属大环主体分子，它们具有形状及空腔大小可控的优越特点。但是，由于Pt金属大环较强的离散性和动态可逆性，使得基于Pt金属大环的主客体识别体系很难建立，进一步限制了其在构筑功能超分子结构及材料中的应用。因此，本申请项目拟建立一类新的Pt金属大环主客体分子识别体系，并进一步探索这类主客体识别体系在构筑机械互锁机构，发光材料，超分子聚合物软材料，可控自组装体以及药物控释体系中的应用。

As an important research field of supramolecular chemistry, the macrocyclic host-based host–guest molecular recognition is always a hot topic among supramolecular chemists. The arrival of any novel kind of macrocyclic host-based molecular recognition system can significantly meet the research needs of host–guest chemistry and further enrich the field of supramolecular chemistry. Platinum(II)-based self-assembled metallacycles, which are constructed through coordination interactions, are a class of discrete macrocycle hosts with controllable cavity size. Because of the dynamic nature of platinum(II) metallacycles, it is difficult to establish platinum(II) metallacycle-based host–guest recognition systems, further limiting their applications in construction of functional supramolecular structures and materials. Therefore, this project will focus on the establishment of platinum(II) metallacycle-based host–guest recognition systems and further exploration of their applications in the construction of mechanically interlocked molecules, luminescent materials, supramolecular polymers, controllable self-assembly and drug release system.