利用静电纺丝纳米纤维为基体材料制备三维电纺气凝胶是近几年静电纺丝领域研究的热点，三维电纺气凝胶保留了静电纺丝纳米纤维的基本优点，且形状可控，具有优异的吸附性能。但是，目前电纺气凝胶的研究仍处于起步阶段，仅通过改变制备电纺气凝胶的原料来实现不同用途。为了进一步拓宽其应用领域，对电纺气凝胶进行表面改性将是电纺气凝胶的未来发展方向。因此，本项目首先利用静电纺丝再生纤维素纳米纤维为原料，制备具有高孔隙率、高表面积、均匀孔径分布、低密度及优良力学性能的电纺再生纤维素气凝胶，然后通过原子转移自由基聚合（ATRP）方法对其进行表面改性，并探索改性后电纺气凝胶在酶固定化领域的应用。本项目首次提出利用ATRP方法表面改性电纺气凝胶，为电纺气凝胶未来研究发展提供了新思路；另外，将改性电纺气凝胶应用到酶固定化领域，对开发新型、高效的酶固定基体材料具有重要指导意义。

Recently, 3D electrospun aerogel fabricated by short electrospun nanofibers has become a hotspot in electrospinning field. 3D electrospun aerogel retains most advantages of the electrospun nanofibers, besides, it has many distinguished features, such as tunable shape and excellent absorption property. However, researches on 3D electrospun aerogel are still at their early stage, i.e. using bulk materials with different properties to achieve different applications. In order to broaden the applications field of the 3D electrospun aerogels, surface modification would be an important developing direction. In this project, we aimed to prepare 3D electrospun aerogels with high porosity, high surface area, uniform pore distribution, low density and good mechanical properties from electrospun regenerated cellulose nanofibers. Subsequently, atom transfer radical polymerization (ATRP) method will be used to surface modify the 3D electrospun regenerated cellulose aerogels and their potential application in enzyme immobilization field will be explored. This project, for the first time, proposes the concept of the ATRP surface modification of 3D electrospun aerogel, which provides a new stratagem to the future development of 3D electrospun aerogel; in addition, it is a significant guiding for developing novel and highly effective matrix materials for enzyme immobilization.