醇胺化反应是制备取代胺类化合物的重要方法，基于醇胺化反应的清洁、高效催化体系研究具有重要的学术意义和应用价值。当前醇胺化反应主要以醇和胺为原料进行，如果能够直接以硝基苯为反应原料与醇一锅法制备取代胺无疑将是该反应的最佳选择。遗憾的是，已有的催化体系需要使用过量的醇作为还原剂。丙三醇是生物柴油的主要副产物，也是制备甘油醛的主要原料，将丙三醇转化成高附加值的化学品是近年来研究的热点。通过硝基苯-醇-丙三醇制备取代胺类化合物和甘油醛是一条经济且环境友好的理想路线。在已有工作基础上，我们将通过对多相催化材料制备关键要素的调控，获得对基于化学计量丙三醇为氢源、硝基苯为原料的醇胺化反应的高效多相催化体系。开展系统的催化剂表征和反应机理研究，明确制备方法-催化剂结构-反应性能-反应机理的基本关系。这一研究将拓展多相催化剂应用领域并为取代胺类化合物和甘油醛清洁制备提供基础研究支持。

Alcohol amination reaction is one of the major methods for N-alkyl amine synthesis. The study of clean and economic synthesis of N-alkyl amine using alcohol as alkylation reagent possesses both scientific and practical significance. Normally, alcohol and amine are the starting materials for the alcohol amination reaction. It would be the best choice if nitrobenzene could be directly used as the starting material without pre-reduction. However, excess amounts of alcohol was used currently which makes it uneconomic and ester as byproduct was produced. The glycedrol is the main byproduct in the biodiesel generation and the starting material in glyceraldehyde synthesis.Recently, it is of great interest to transform glycerol to high value added chenmicals. It might be an ideal route if we can synthsis the N-alkylamines and glyceraldehyde by the one-pot reaction from nitrobenzenes, alcohols and glycerol. This process is economical and evironment friendly. Based on the past work, a series of heterogeneous catalysts with different structures and activities will be prepared for the alcohol amination using nitrobenzene as starting material and stoichiometric glycerol as hydrogen source. The catalysts will be characterized systematically and the relationship among preparation method, catalyst structure, catalytically active position and reaction mechanism will be revealed. The implementation of this project will promote the utilization of heterogeneous catalyst in fine chemical synthesis and support the development of clean and economic N-alkyl amines and glyceraldehyde synthesis.