回声定位蝙蝠所发出的CF-FM信号既用于回声定位以感知生存环境，也用于种内和种间的通讯，具有类似于人“视觉”和“声语言”的功能。目前人们对大脑怎样加工复杂声所知甚少，一直在寻找建立在细胞和回路基础上的行为相关声信号加工的机制方面的证据。本项目将采用神经电生理等方法，研究“CF-FM蝙蝠下丘对行为相关声信号的加工模式及生理机制”，探讨“CF-FM信号加工模式的种属特异性，电生理机制，从下丘向高位中枢投射的信息通道，以及双耳听觉在两种反应模式中的作用”。所获得的研究结果可为进一步了解行为相关声信号的加工模式及机制，以及为临床听觉中枢功能异常的诊断等提供某些依据和参考。

The CF-FM sound signal emitted by echolocating bats is a complex and echolocation behavior-related sound signal and is used both to perceive living surrounding and to communicate between the bats within species and interspecies, which it has the similar functions to the human vision and speech sound. Up to now, it is known very few for how to process the complex sound signals in our brain, but seeking the evidence for the mechanism of behavior-related sound signal processing based on the neurons and neural circuits always does not given up. So, we shall attempt to investigate the pattern and physiological mechanism of echolocation behavior-related sound signal processing in the inferior colliculus (IC) of CF-FM bat in present proposals using the electrophysiological methods and probe the species-specific property of CF-FM signal processing, electrophysiological mechanism, auditory information channel from the IC to the higher auditory structures and the role of interaural property in the single-on and double-on responders or neurons. The results obtained in present study provide possibly some new knowledge and experimental evidences for further understanding the mechanism of behavior-related sound signal processing and the diagnosis of hearing disease in the central auditory structures.