前期研究证明，MR成像技术可清晰显示足踝精细解剖结构及损伤的影像学表现。本项目利用MR成像技术，研究新鲜足踝尸体标本的正常断层解剖及影像学、组织学表现，主要研究足伸肌腱、屈肌腱、跗骨间韧带、Lisfranc韧带、跖骨间韧带、以及踝关节的跟腱、外侧副韧带、内侧三角韧带等结构，阐明足踝的解剖特点与影像学、组织学表现的相关性，为影像诊断和外科治疗提供实用的断层解剖学依据；对大体标本进行模拟损伤实验，并行MR检测，研究足踝不同部位损伤机制与影像学表现，阐明损伤机制和MR影像特点的相关性，为足踝损伤的诊断治疗提供有价值的影像学依据；研究国人正常足踝MRI解剖结构和不同部位损伤机制及其MR影像特点，旨在早期发现其细微解剖结构变化和明确损伤部位及类型，并从分子水平无创地监测损伤的发生发展过程，为足踝损伤的早期诊断、治疗及功能恢复提供科学精准的解剖学和影像学依据，为损伤的基础研究和临床应用奠定基础。

The aim of this study is using magnetic resonance imaging (MRI) to investigate the normal cross-sectional anatomy and injury mechanism of the foot and ankle. We will first study the normal cross-sectional anatomy in correlation with MRI appearance and histologic analysis, using cadaveric foot and ankle, and correlate the MRI appearances with large histological section to demonstrate the flexor tendons, the extensor tendons, the intertarsal ligaments, the Lisfranc ligament and the intermetatarsal ligaments , and Achilles tendon, the lateral ligament, the deltoid ligament of the ankle. The anatomic and histologic features of the foot and ankle and their functional relationship will be demonstrated with MR images. Next, we will study the injury mechanism of the foot and ankle and their MRI features by creating the injury to the foot and ankle in cadaver, to provide the theoretical basis for evaluation and interpretation of the foot and ankle injuries; to reveal the relationship between injury mechanism and the MRI features. Finally, we will study the foot and ankle injury in clinical setting to study their MRI features. Our goal is using the MRI, a noninvasive technique to define the relation between the subtle anatomic changes and the injury mechanism, to monitor the development and the nature progression of the foot and ankle injury, to lay the foundation for future basic research and clinical applications on foot and ankle injury at the molecular level.