氧化性反应条件下的不对称钯催化体系的发展是近年来有机化学中富有挑战性的热点研究领域之一。本项目设计了一个由Pd(II)络合物、Br?nsted acids和phosphoramidites组成的手性的三元协同催化体系 ，并拟研究该协同催化体系在氧化性反应条件下的不对称semipinacol 重排反应以及烯丙位C-H键直接官能团化反应中的应用。相关反应的机理将通过设计适当的控制实验等手段来进行研究。项目的顺利实施将会发展出一类适用于氧化性反应条件下的新的不对称钯催化体系，为相关手性化合物的合成和有机合成化学提供新的工具。

The development of?asymmetric palladium catalytic systems compatible?with oxidative reaction conditions has recently been a challenging research focus in organic chemistry. This project designs a ternary chiral cooperative catalytic system consisting of Pd(II)complexes,?Br?nsted acids and phosphoramidites，the application of which would be studied in semipinacol rearrangements and direct allylic C-H bond functionalization under oxidative reaction conditions. The mechanism of these reactions would be investigated by methods such as the rational design of control experiments. The implementation of this project would provide a new type of asymmetric palladium catalytic system compatible with oxidative conditions, which would serve as new synthetic tools for the synthesis of relevant chiral compounds and synthetic organic chemistry.