作为重要的环境因子，温度影响植物器官生长、发育的各个方面，但目前人们对植物感受温度及其对植物发育调控的分子机制仍了解甚少。我们从拟南芥突变体库筛选到一个莲座叶异常、花茎显著缩短、角果簇生的突变体clustered siliques (cls)，其突变表型依赖于高温环境。通过图位克隆的方法克隆了CLS基因，它编码一个推测的类激酶蛋白。CLS基因家族是植物所特有的，在拟南芥中有13个成员。目前尚未见它们在植物温度响应和器官发育调控方面的功能报道。我们将利用遗传学、生物化学、细胞生物学和分子生物学等方法，研究CLS在温度调控植物地上器官发育中作用的生化和分子机制，鉴定CLS互作蛋白和其控制途径的重要信号分子，以期建立一条CLS介导的植物高温响应和器官发育调控的信号途径。

As a critical environmental factor, the temperature influences various aspects of plant growth and development. However, the molecular mechanisms underlying how temperature affects plant morphogenesis are largely unknown. By genetic screening of Arabidopsis mutants defective in aerial organ development, we identified a mutant, named clustered siliques (cls), that displayed aberrant leaves and severely compressed internodes of inflorescence stem in a thermo-sensitive manner. We isolated the CLS gene by map-based cloning and found that CLS encodes a putative kinase-like protein. CLS gene family is plant-specific and contains 13 members in Arabidopsis genome. Using genetic, biochemical, cytological and molecular approaches, we will dissect the molecular mechanisms of how thermal signal affects CLS and how CLS regulates organ growth and development at transcriptional or post-transcriptional levels, and we will further identify the CLS-interacting proteins and new molecules in the CLS pathway. These works will further our understanding of the molecular basis of how plant integrates thermal signal into organ morphogenesis.