磁性离子印迹材料(MIIM)因具有较好的选择性，在样品前处理领域具有良好的应用前景，但其萃取性能与材料的制备方式密切相关，为获得印迹位点更丰富、传质效率更快、耐干扰能力更强的MIIM，在MIIM结构中引入合适的多孔材料并改进制备方法至关重要。本项目拟采用高孔隙度的共价有机骨架材料(COF)作为支撑骨架，通过COF单体与离子印迹聚合物同时在磁性纳米材料表面进行共价键合的方式，制备具有高孔隙通透性、高选择性与快速磁分离性能的磁性离子印迹COF复合材料。这种制备方法可通过调控COF单体与印迹聚合物的比例，改善材料的选择性，并获得一定的孔隙度，既能增强模板离子的传质能力，也能限制大分子干扰物进入骨架结构中，增强材料的耐干扰能力。这种磁性印迹COF材料具有高效高选择性萃取分离痕量物质的潜力，可构建基于COF的离子印迹-磁固相萃取前处理技术，有助于解决实际分析领域复杂基体中痕量元素的分离分析难题。

Magnetic ion imprinted material (MIIM) has a great application prospect in the field of sample pre-treatment due to its good selectivity, while the extraction performance of MIIM is closely related to their preparation method. In order to obtain MIIM with richer imprinting sites, faster mass transfer efficiency and stronger interference resistance, it is crucial to introduce appropriate porous materials into the MIIM structure and improve the preparation method. This project intends to use covalent organic frameworks (COF) with high porosity as the supporting skeleton, and prepare magnetic ion imprinted COF composite by covalently binding COF monomer and ion-imprinted polymer on the surface of magnetic nanomaterials, which finally have high porosity and high selectivity for fast magnetic separation. By regulating the ratio of COF monomer and ion imprinted polymer, this preparation method can improve the adsorption selectivity of the materials toward template ions and obtain certain porosity, and the entry of macromolecules into the framework structure can be restricted by porosity control to enhance interference resistance. This kind of magnetic ion imprinted COF composite has great efficiency in the extraction of analytes even in trace amount, and a sample pretreatment technique by utilizing COF materials for ion imprinted magnetic solid phase extraction can be established, which have great practical significance for resolving the difficulty in separation and analysis of trace elements in complex matrices.