青藏高原大规模变形的研究对于探索高原的隆升机制具有至关重要的作用。然而，以往的研究要么仅限于岩石圈自身的作用，要么仅限于地幔对流产生的作用，要么存在模拟结果分辨率不高等问题。本研究将使用高分辨率地震层析成像模型，用岩石圈和地幔动力学联合模拟方法，把岩石圈自身的作用力和地幔对流产生的作用力有机结合起来，进而获得全球应力场、全球应变率和速度场；然后，用观测的全球应力分布、全球应变率和速度矢量检验模拟结果。在获得满足这些验证条件模型的基础上，精细刻画青藏高原地区应力场、速度场和应变率分布，探讨高原变形的原因。优点：1）使用该联合模拟方法把青藏高原深部运动和浅部大规模变形结合起来；2）在全球尺度下探讨青藏高原大规模变形的原因,可以避免局部区域数值模拟在设置边界条件方面的限制。这对于正确认识印度-欧亚板块碰撞和青藏高原隆升的机制具有重要意义，同时也对认识岩石圈变形以及壳幔耦合的相互作用有帮助。

The large-scale deformation in the Tibetan Plateau has a crucial role to explore the mechanism of the uplifting of the plateau. However, previous studies have either limited to the force of the lithosphere, either limited to the force only produced by mantle convection, or the low precision of results etc. It is difficult to calculate the stress because we need take into account the effects both topography and shallow lithosphere structure as well as tractions originated from deeper mantle convection. We investigate the problem by separating these contributions into two parts: (1) the contribution of gravitational potential energy (GPE) differences, and (2) the contribution of coupling with 3-D mantle flow. The contribution of GPE is calculated from topography and lithosphere structure. The basal tractions are derived from a tomography model with radial viscosity variations. Tomography models provide estimates of density structure, which drives flow. Tractions arising from 3-D mantle convection act as a basal boundary condition in the lithosphere finite element model. The solutions of GPE and tractions are then combined to obtain the full model. A successful lithosphere-mantle coupling model for the Earth will satisfy observations of plate motions, intraplate stresses, and the plate boundary zone deformation. In this study, we use the World Stress Map, the Global Strain Rate Model, and the No-Net-Rotation (NNR) surface velocity vectors to constrain the models. Based on the best-fit model, we delineate the strain rate, stress field and velocity field. We discuss the reason of the large-scale deformation in the plateau. Advantages: (1) the joint method will combine the large-scale shallow crustal deformation with the deep movements of the Tibetan Plateau; (2) on a global scale, we discuss the mechanics of the large-scale deformation in the Tibetan Plateau and avoid anthropogenic setting the boundary conditions to a region model. This work will improve us understand the driving forces of the India-Eurasia collision and the uplifting of the Tibetan Plateau. This work will also improve us understand the deformation of lithosphere and the effects of the crust-mantle coupling.