环境中广泛分布的多环芳烃具有毒性强、浓度低的特点，而官能团取代多环芳烃(X-PAHs)的致癌和致突变性可增大至母体的数十万倍，迫切需要针对环境中浓度极低的X-PAHs进行分析和监控。固相微萃取(SPME)作为一种集采样、萃取和进样于一体的样品前处理技术，具有绿色环保、自动化程度高、抗基质干扰能力强和富集效率高等优点,十分有潜力用于X-PAHs的高灵敏分析。本项目拟制备具有高比表面、特定孔径和官能团的功能化共轭多孔聚合物，并通过不同方法将其发展为新型SPME探针涂层材料；进而通过吸附热力学和动力学模型、理论计算与富集实验相结合的方法，探明材料的孔径、官能团、比表面积与其对X-PAHs吸附性能之间的构效关系；最终，用于水体和动植物活体中X-PAHs的高灵敏分析。本项目研究有利于探明共轭多孔聚合物的微观结构与吸附性能之间的关系，对拓展SPME应用范围及开发高灵敏环境分析技术也有重要的推动作用。

The widespread polycyclic aromatic hydrocarbons (PAHs) in environment show the properties of strong toxicity and low concentration. Nevertheless, the carcinogenicity and mutagenicity of X-substituted polycyclic aromatic hydrocarbons (X-PAHs) are likely to be a hundred thousand times higher than their parent, resulting in urgent need for the analysis and monitoring of X-PAHs with ultralow concentrations. Solid phase microextraction (SPME), as a kind of sample pre-treatment technique integrating sampling, extraction and injection into one step, has demonstrated the advantages of high level automation, strong anti-interference capability and efficient enrichment, which is very promising to be employed for the high-sensitive analysis of X-PAHs. In this project, a series of functional conjugated porous polymers (CPPs) with high surface area, unique pore structure, different functional groups will be synthesized and prepared as novel SPME fiber coatings by different methods. Moreover, the structure-performance relationship of CPPs between their pore structure, functional group, surface area and adsorption efficiency will be investigated based on the adsorption thermodynamics and kinetics, theoretical calculations and enrichment results. Finally, the CPPs with excellent performance will be designed and synthesized for the preparation of high-efficient SPME fibers, which will be used for high-sensitive analysis of X-PAHs in water sample, as well as in vivo experiment. This project will not only be of great importance to expand SPME application and develop methods with high sensitivity, but also be beneficial for the study of relationship between the microstructure and adsorptive property of CPPs.