钯催化烯丙基酯脱羧烯丙化反应是一种高效的有机合成工具，是当前合成化学研究的热点和前沿，在药物、天然产物、有机功能材料的合成和制备方面有重要应用。本申请拟开展钯催化烯丙酯与碘叶立德的脱羧烯丙化反应的研究，合成一系列烯丙基化合物，丰富烯丙基化合物的种类，进一步发展有机合成方法学，为今后的研究及应用提供理论基础。主要内容如下：（1）通过对反应底物设计和反应条件的优化，发展烯丙基酯和碘叶立德脱羧烯丙化反应的方法和技术。（2）将该方法和技术应用于生理活性天然产物和药物的合成。总之，通过该项研究，将发现并揭示烯丙酯脱羧烯丙化反应所表现出的新现象和规律，拓宽反应的应用新途径，并不断丰富有机化学的内涵。从而进一步促进和实现资源高值化及绿色化利用，并为实现其工业化提供理论依据和实践基础。

Palladium-catalyzed allyl esters decarboxylative allyllation reactions have had a profound impact on the synthesis of pharmaceuticals, biologically active natural products, and materials. This project focuses on palladium-catalyzed allyl esters decarboxylative allylation reactions with Iodonium ylides for the synthesis various of allylate. This research will rich the library of allylate and develop a new organic sythesis methodology, which provides theoretical guidance for future research and applications. The mian contents include:(1) Through design reagents and optimization of reaction conditions, development palladium-catalyzed allyl esters interceptive decarboxylative allylation reactions sythesis methodology (2)Applications of the method to the synthesis of physiologically active substances and drugs. To sum up, the research project will turn out the new phenomena and law of allyl esters interceptive decarboxylative allylation reactions, extend this method applications in organic synthesis, and to rich the connotation of oganic chemistry. So as to implement resources of high value and use of green, and provide the theoretical foundation and practical basis for its industrialization.