针对导致传统釜式反应器中Wittig-Horner液液相转移催化反应的收率和选择性偏低的关键原因之一的相间传递限制问题，本项目采用微通道反应器强化液液传质过程，利用实验和数值模拟相结合的方法，瞄准如何实现传递与反应协同机制及过程强化的关键科学问题，系统研究微通道内Wittig-Horner液液相转移催化反应的动力学规律，通过对比本征反应动力学与表观反应动力学的差异和分析相间传质、本征反应动力学和表观反应动力学的相互作用关系，掌握该类型反应从本征动力学到表观动力学的演变规律，揭示反应的过程机理；建立基于 CFD 的两相流动-相间传质-反应过程耦合模型和数值模拟计算方法，利用耦合数值模拟，阐释两相流动-相间传质-反应过程三者间的耦合相互作用规律，揭示反应过程的定量调控机制，从而为面向液液相转移催化反应的微通道反应器的科学设计、优化改进、操作调控和相关工业应用开发奠定必要的理论和技术基础。

The low reaction yield and selectivity of Wittig-Horner liquid-liquid phase transfer catalyzed reaction in conventional stirred reactors are partially resulted from inefficient interphase mass transfer. Microchannel reactor is thus employed to enhance the liquid-liquid mass transfer process in this proposal. In order to achieve synergism between interphase mass transfer and the intrinsic reaction kinetics, and hence the intensified result for the Wittig-Horner liquid-liquid phase transfer catalyzed reaction in the microchannel reactors, a combined experimental and numerical study is performed. Reaction kinetics of this two-phase reaction in the microchannel reactor is systematically investigated. The evolution mechanism from its intrinsic kinetics to apparent kinetics can be understood by examining the differences between the intrinsic kinetics and apparent kinetics and an in-depth analysis of the interactions among interphase mass transfer, intrinsic kinetics and apparent kinetics. As such, the process mechanism of this two-phase reaction can be revealed. A CFD model coupling two-phase flow, interphase mass transfer and intrinsic kinetics is developed and numerically solved, which is then adopted to simulate the experimental cases and beyond. The coupled numerical simulations are used to interpret the interactions among two-phase flow, interphase mass transfer and reactions, and to further reveal the quantitative regulation mechanism of Wittig-Horner liquid-liquid phase transfer catalyzed reaction. The project is expected to lay solid theoretical and technical foundations for the scientific design, improvement, optimization, operation and relevant industrial application development of liquid-liquid phase-transfer-catalyzed-reaction-oriented microchannel reactors.