由于对新型有机磷阻燃剂（OPFRs）需求的持续上涨，此类化合物已在室内灰尘中检出，其水平与多溴联苯醚（PBDEs）相当；细胞、动物实验表明新型OPFRs具有潜在健康危害。目前对新型OPFRs在室内环境中污染特征及释放机制的认知甚少，严重制约了这类污染物的人体暴露和健康风险评估。本项目针对室内环境介质中的几类重要新型OPFRs，在建立高灵敏度痕量分析方法的基础上，研究其室内环境中的污染水平、特征及季节变化规律，阐明不同环境条件对其污染水平及特征的影响；利用模拟腔体实验，研究新型OPFRs从产品向室内环境的释放过程及其机制，阐明释放速率与温度、时间和理化性质的关系；结合实际环境中发现的污染特征，明确室内环境中新型OPFRs的来源以及不同来源的贡献度；根据人体活动规律，评估新型OPFRs的外暴露水平。项目可为室内环境中新型OPFRs的来源解析提供新的认知，并为该类新型污染物的管控和削减提供依据。

As the demand for emerging organophosphorus flame retardants (OPFRs) continues to rise, those compounds have been detected in indoor dust at levels comparable to conventional OPFRs; cell and animal experiments have showed that emerging OPFRs have potential health hazards. However, little is known about the pollution characteristics and release mechanism of emerging OPFRs in the indoor environment, which seriously restricts the human exposure and health risk assessment of such pollutants. This project plans to study several important emerging OPFRs in the indoor environment matrices, based on high sensitivity of trace analysis method for emerging OPFRs, the pollution levels, characteristics and seasonal variations of those target compounds in the indoor environment will be studied; the impacts of different environmental factors on the pollution levels and characteristics of emerging OPFRs will be clarified; simulated test chamber experiments will be applied to study the release processes and mechanism of emerging OPFRs from products to the indoor environment and clarify the relationships between release rates and temperature, time and physicochemical properties; combined with the pollution characteristics found in the actual environment to verify the sources of emerging OPFRs and the contributions of those different sources in the indoor environment; according to the laws of human activities, the external exposure levels of emerging OPFRs will be assessed. The project is expected to provide new knowledge for the source analysis of emerging OPFRs in the indoor environment as well as a basis for its control and reduction.